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Profluent

20+ Best Alternatives to Profluent in 2026

Frontier AI models for programmable biology and protein design

Looking for an alternative to Profluent? Below are 20 AI startups working in the same space — ranked by our Neuron score so the most credible options come first. Each card shows what makes the tool a viable substitute, pricing signals, and funding stage.

  1. 1

    Recursion

    Undisclosed

    Pioneering AI-driven solutions in drug discovery to radically improve lives.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  2. 2

    Chai Discovery

    $200M

    Engineering better molecules using artificial intelligence for drug-like antibody design against challenging targets with atomic precision.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  3. 3

    Tempus

    Undisclosed

    Tempus is an AI-powered precision medicine company transforming healthcare through data-driven insights and genomic testing.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  4. 4

    Insilico Medicine

    Undisclosed

    Accelerating drug discovery and development through generative AI and advanced bioinformatics platforms.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  5. 5

    Lunit

    Undisclosed

    Conquer cancer through cutting-edge AI for earlier detection and more precise oncology treatments.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  6. 6

    Enveda

    Undisclosed

    Enveda is learning from life to discover medicines 4X faster than the industry average by unlocking nature's hidden chemistry.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  7. 7

    SandboxAQ

    Undisclosed

    Transforming the world with AI and advanced computing, applying quantitative AI to solve complex challenges in various industries.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  8. 8

    Owkin

    Undisclosed

    Pioneering biological artificial superintelligence to automate R&D and connect research directly to patient care.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  9. 9

    Iambic Therapeutics

    Undisclosed

    Leveraging AI technologies to accelerate the discovery and development of optimised medicines for challenging diseases.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  10. 10

    Atomwise

    Undisclosed

    Our AI superplatform explores the vast universe of chemical space to discover novel, drug-like molecules unseen by others.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  11. 11

    Xaira Therapeutics

    Undisclosed

    Pioneering transformative artificial intelligence to discover and develop the next generation of life-changing medicines.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  12. 12

    EvolutionaryScale

    Undisclosed

    Frontier AI for the life sciences, enabling scientists to understand, imagine, and create proteins.

    Why it's similar: Shares categories with Profluent — AI Healthcare, Drug Discovery.

    💵 Enterprise · Contact sales

    View alternative →
  13. 13

    OpenEvidence

    $735M

    AI medical assistant for clinicians

    Why it's similar: Shares categories with Profluent — AI Healthcare.

    💵 Free

    View alternative →
  14. 14

    Hippocratic AI

    $461M

    Safe AI agents for healthcare

    Why it's similar: Shares categories with Profluent — AI Healthcare.

    💵 Enterprise · Contact sales

    View alternative →
  15. 15

    Elicit

    $22M

    AI research assistant for scientists

    Why it's similar: Shares categories with Profluent — AI Healthcare.

    💵 Free

    View alternative →
  16. 16

    Ambience Healthcare

    $243M

    The AI operating system for healthcare

    Why it's similar: Shares categories with Profluent — AI Healthcare.

    💵 Enterprise · Contact sales

    View alternative →
  17. 17CH

    Chapter

    $200M

    AI-driven Medicare navigation platform building the trust layer between seniors and technology.

    Why it's similar: Shares categories with Profluent — AI Healthcare.

    💵 Pricing not listed

    View alternative →
  18. 18

    Suki AI

    $70M

    AI voice assistant for clinicians

    Why it's similar: Shares categories with Profluent — AI Healthcare.

    💵 Enterprise · Contact sales

    View alternative →
  19. 19AP

    AppliedAI

    $55M

    Agentic AI for back-office automation in regulated industries

    Why it's similar: Shares categories with Profluent — AI Healthcare.

    💵 Pricing not listed

    View alternative →
  20. 20CA

    Carecode

    $4.3M

    AI agents for healthcare contact centers, accessed via WhatsApp

    Why it's similar: Shares categories with Profluent — AI Healthcare.

    💵 Pricing not listed

    View alternative →

Frequently asked questions

What are the best alternatives to Profluent?

The top-ranked alternatives to Profluent on NeuronFeed are Recursion, Chai Discovery, Tempus, Insilico Medicine, Lunit. Rankings are based on our Neuron score, which weighs funding, momentum and editorial signal.

Is there a free alternative to Profluent?

Yes — EvolutionaryScale, OpenEvidence, Elicit offer a free plans. See the pricing column for each alternative above.

How is this list ranked?

We rank alternatives by shared categories with Profluent, then by our proprietary Neuron score (0–100) which combines funding, team quality, momentum, and editorial input. The list refreshes every 30 days.

Profluent vs Recursion — which is better?

It depends on use case. Recursion (Pioneering AI-driven solutions in drug discovery to radically improve lives.) is the #1-ranked alternative. See the full side-by-side at /compare/profluent-vs-recursion.

Contextual paths to related AI startups, deals and rankings.