Trially is a Kansas City-based clinical trial technology startup that uses agentic AI to solve the patient-recruitment bottleneck that delays most studies. Its platform reads medical data to instantly match patients with appropriate trials, then deploys Margo, an agentic AI agent, to convert qualified matches into enrolled participants by engaging individuals through voice, text, and email and handling pre-screening, scheduling, and follow-up. The product spans three integrated offerings: Trially Match for instant subject matching, Trially Connect for Margo-driven outreach and pre-screening, and Trially Intelligence for proactive study-feasibility alerts and analytics. By automating the slowest, most manual parts of enrollment, Trially aims to multiply study enrollment for sites and sponsors. It raised a $4.7M seed round in September 2025 led by Flyover Capital, with Atria, Alpaca, Blu Ventures, and others.