Best Infrastructure AI Startups in United States
100 startups match both filters.
Databricks
VerifiedThe data + AI company
Figure AI
VerifiedGeneral-purpose humanoid robots
Upscale AI
Pure-play AI networking infrastructure
VAST Data
Unifying software layer for AI infrastructure
Quantinuum
World's largest integrated quantum computing company
Scale AI
VerifiedData labeling and AI infrastructure platform powering frontier models for enterprises and governments.
VoltaGrid
VoltaGrid provides hybrid power solutions that reduce emissions, optimize energy loads, and lower costs for industrial applications and data centers.
Groq
VerifiedFastest AI inference on the planet
Crusoe
VerifiedSustainable AI cloud infrastructure
Cerebras Systems
VerifiedWafer-scale AI chips for unprecedented speed
CoreWeave
The Essential Cloud for AI, purpose-built to power pioneers' most complex workloads with next-generation infrastructure and intelligent tools.
DataRobot
The only unified agent workforce platform built for enterprise outcomes, not endless pilots.
Lambda
VerifiedGPU cloud for AI teams
Tenstorrent
Tenstorrent provides high-performance AI compute solutions, from cards and workstations to scale-out servers, powered by flexible, open-source IP.
SambaNova
The fastest AI inference platform, purpose-built for agentic AI with custom dataflow technology and three-tier memory architecture.
OpenRouter
A unified API gateway to 400+ LLMs across 60+ providers
Ndea
Frontier AI lab building AGI through deep learning-guided program synthesis.
Parallel
Web search and research API purpose-built for AI agents
Emerald AI
Turns AI data centers into flexible grid assets that ease power demand
Unconventional AI
Reinventing the computer with brain-inspired, energy-efficient AI hardware
Inferact
Commercial inference engine from the creators of vLLM
Story Protocol
Programmable IP blockchain for tracking and monetizing AI-era content
Mercor
Mercor is an AI-powered platform connecting top-tier remote AI talent with companies shaping the future of artificial intelligence.
RadixArk
Open infrastructure for frontier AI, built on SGLang
io.net
Decentralized GPU cloud network aggregating compute for AI and ML workloads
FriendliAI
Fast, cost-efficient generative AI inference for any model
EnCharge AI
Analog in-memory AI chips that slash energy use for inference
DeepInfra
High-throughput, low-cost AI inference cloud
MatX
Chips built from the ground up for frontier large language models
Hugging Face
The AI community building the future of machine learning.
Skyflow
Skyflow provides runtime AI data control, securing sensitive data across datastores, models, and AI agents.
Standard AI
Computer vision for autonomous checkout in physical retail.
/dev/agents
An operating system purpose-built for the era of AI agents.
Mem0
The memory layer for AI agents and personalized AI applications
GridCARE
Physics-based AI that unlocks hidden power-grid capacity to accelerate AI data centers
BentoML
Unified inference platform to run AI at scale
Genmo
Open-source generative AI for video, building state-of-the-art text-to-video foundation models.
KERNEL
Crazy fast, open source infra for AI agents to use the Internet
Lamini
Enterprise platform for tuning and running custom LLMs
Eridu
Rebuilding the AI data center network to break the interconnect wall
Parasail
Pay-per-token AI inference supercloud that puts developers in control
Chalk
AI data platform delivering real-time context for models and agents
Vana
Decentralized network for user-owned data to train AI models
Coval
Simulation and evaluation platform for voice and chat AI agents, modeled on self-driving car testing.
Luminal
Making AI run fast on any hardware
Manufact (formerly mcp-use)
Open source SDK & cloud infrastructure for MCP Servers & ChatGPT Apps
SF Compute
A real-time marketplace for AI compute
Phaidra
AI agents for AI factories, optimizing complex power, cooling, and workload management systems to maximize tokens per watt.
Dedalus Labs
Compute substrate for AI agents
Native
Security-by-design control plane for multi-cloud and AI infrastructure
Hyperbolic
Open-access AI cloud for compute and inference
Vectara
The Unified Context Layer for building AI agents across SaaS, VPC, and On-Prem environments.
Runpod
The fastest way to deploy and scale AI workloads with on-demand GPUs and serverless infrastructure.
truthsystems
Automatically blocking risky behavior with real-time governance agents
Qualified Health
Enterprise generative AI infrastructure and governance for health systems
Liquid AI
Efficient general-purpose foundation models built for edge, on-device, and cloud deployment at every scale.
Lightmatter
Photonic chips that move data with light for next-gen AI data centers
Boundary (BAML)
BAML, a programming language and toolchain for building type-safe, structured-output LLM applications.
Ragie
Fully managed RAG-as-a-Service for developers
Oximy
See and control all AI activity across your enterprise
Terminal Use
Vercel for background agents
Sponge
Financial infrastructure for the agent economy
Rubric AI
Reasoning and verification infra for AI
Moda
The monitoring layer your AI agents need
The Token Company
Compression middleware that improves LLM outputs
IncidentFox
AI SRE agent that triages, coordinates, and fixes production incidents
Orthogonal
Agentic Payments for APIs
RunAnywhere
The default way of running on-device AI at Scale
Klaus AI
Fast and Safe OpenClaw on the cloud
Captain
Give AI agents accurate knowledge search that scales
Autumn AI
Stalk your prospects at scale
Minicor
RPA platform for deploying AI into legacy desktop systems
ProjectX
Infinity: the first OS where humans and agents work with no limits
Interfaze
AI model built for deterministic developer tasks
Ardent
Database sandboxes for Agents
Wato
Shared memory, tools, and workflows for agents across teams
Scope
The infra layer for AI agent experience
TakeCareOS
Building infrastructure for AI-native care providers
GovGuard
AI Infrastructure for Government Agencies
Context.dev
We give AI agents realtime web context
Hyperspell
Memory for AI Agents
SF Tensor
Infrastructure for AI labs to focus on research
Sciloop
Expert STEM reasoning data for frontier AI labs
AgentMail
Email Inboxes for AI Agents
Modelence
The full-stack platform for agentic development
Imprezia
The World's First AI Ad Network
LLM Stats
Independent AI evaluations lab
Runloop
Enterprise-grade cloud infrastructure and devboxes for AI coding agents
MemryX
Energy-efficient edge AI accelerator chips for on-device inference
Anyscale
Production-scale AI infrastructure powered by Ray for distributed training, data curation, and batch inference.
Overshoot
AI Infra for real-time vision applications
Chamber
The AIOps Agent for ML Teams
Salus
Guardrails to validate your agent's actions before they execute
StableBrowse
Browser Layer for AI agents
Anon
Authentication and automation infrastructure so AI agents can act on the web
Banana
Inference hosting for AI teams who ship fast and scale faster.
Zibra Labs
Distributed Compute for AI
Nerviom
AI Autopilot for Infrastructure Permitting
Neurophos
Metasurface optical processors for exaflop-scale AI inference
Modular
A unified AI inference platform for high-performance, portable compute, enabling full optimisations from GPU kernel to API endpoint.