Best Infrastructure AI Startups in United States
48 startups match both filters.
Hugging Face
The AI community building the future of machine learning.
Anyscale
Production-scale AI infrastructure powered by Ray for distributed training, data curation, and batch inference.
Quantinuum
World's largest integrated quantum computing company
Modal
High-performance AI infrastructure with sub-second cold starts and instant autoscaling.
Databricks
VerifiedThe data + AI company
Liquid AI
Efficient general-purpose foundation models built for edge, on-device, and cloud deployment at every scale.
DataRobot
The only unified agent workforce platform built for enterprise outcomes, not endless pilots.
Together AI
VerifiedThe open AI cloud
Baseten
Deploy and scale AI models in production with the fastest inference infrastructure.
Lightmatter
Photonic chips that move data with light for next-gen AI data centers
OpenRouter
A unified API gateway to 400+ LLMs across 60+ providers
Positron AI
US-built, energy-efficient AI inference chips designed to challenge Nvidia on performance-per-watt.
DeepInfra
High-throughput, low-cost AI inference cloud
Unconventional AI
Reinventing the computer with brain-inspired, energy-efficient AI hardware
Fireworks AI
VerifiedProduction-grade generative AI serving
TensorWave
AI cloud built on AMD Instinct accelerators, operating one of the world's largest liquid-cooled AMD GPU deployments.
EnCharge AI
Analog in-memory AI chips that slash energy use for inference
Qualified Health
Enterprise generative AI infrastructure and governance for health systems
Figure AI
VerifiedGeneral-purpose humanoid robots
GridCARE
Physics-based AI that unlocks hidden power-grid capacity to accelerate AI data centers
Emerald AI
Turns AI data centers into flexible grid assets that ease power demand
MatX
Chips built from the ground up for frontier large language models
Parasail
Pay-per-token AI inference supercloud that puts developers in control
Eridu
Rebuilding the AI data center network to break the interconnect wall
You.com
The productivity search engine with AI agents.
CoreWeave
The Essential Cloud for AI, purpose-built to power pioneers' most complex workloads with next-generation infrastructure and intelligent tools.
SambaNova
The fastest AI inference platform, purpose-built for agentic AI with custom dataflow technology and three-tier memory architecture.
VAST Data
Unifying software layer for AI infrastructure
/dev/agents
An operating system purpose-built for the era of AI agents.
Mem0
The memory layer for AI agents and personalized AI applications
Story Protocol
Programmable IP blockchain for tracking and monetizing AI-era content
Groq
VerifiedFastest AI inference on the planet
Parallel
Web search and research API purpose-built for AI agents
Inferact
Commercial inference engine from the creators of vLLM
io.net
Decentralized GPU cloud network aggregating compute for AI and ML workloads
SF Compute
A real-time marketplace for AI compute
Crusoe
VerifiedSustainable AI cloud infrastructure
Cerebras Systems
VerifiedWafer-scale AI chips for unprecedented speed
Tenstorrent
Tenstorrent provides high-performance AI compute solutions, from cards and workstations to scale-out servers, powered by flexible, open-source IP.
GMI Cloud
AI-native inference cloud built for production AI workloads on H100, H200 and Blackwell GPUs.
Runloop
Enterprise-grade cloud infrastructure and devboxes for AI coding agents
FriendliAI
Fast, cost-efficient generative AI inference for any model
Hyperbolic
Open-access AI cloud for compute and inference
Exa
VerifiedSearch for AI applications
Upscale AI
Pure-play AI networking infrastructure
KERNEL
Crazy fast, open source infra for AI agents to use the Internet
Luminal
Making AI run fast on any hardware
Chalk
AI data platform delivering real-time context for models and agents