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Madrona Ventures

Active VC
Portfolio Active
4
Latest Terray Therapeutics
Deal flow
$292M
4 rounds
Unicorns
0
≥ $1B valuation
Founded
—
Latest
Jul 2025
Observe

About Madrona Ventures

Venture capital firm tracking 4 AI investments, with focus on AI Agents and US startups. Total tracked deal flow: $292M.

Investment activity

2024–2025
$120M
$156M
1
'24
1
'25

Sector focus

🤖 AI Agents 2
⚙️ AI DevOps 1
💊 Drug Discovery 1
👀 AI Observability 1
🏥 AI Healthcare 1
⚡ AI Productivity 1

Geographic focus

US 3

Portfolio

4

Terray Therapeutics

Generative AI and ultra-high-throughput chemistry for small-molecule drug discovery

Observe

AI-native observability platform built on a data lake to replace Splunk and Datadog

Otto

Autonomous AI travel agent for business travelers

Tektonic AI

Co-investors

8

Hugh Crean

1 shared

Barney Harford

1 shared

Erik Blachford

1 shared

Direct Travel

1 shared

Capital One Ventures

1 shared

Alumni Ventures

1 shared

Sutter Hill Ventures

1 shared

Alexandria Venture Investments

1 shared

Recent rounds

4
Jul 30, 2025 Series C $156M Observe
Oct 17, 2024 Series B $120M Terray Therapeutics
Seed $6M Otto
Seed $10M Tektonic AI