EvolutionaryScale vs Isomorphic Labs
Which Drug Discovery AI tool is better in 2026?
EvolutionaryScale
Frontier AI for the life sciences, enabling scientists to understand, imagine, and create proteins.
Isomorphic Labs
London-based AI drug-design company spun out of Google DeepMind to reimagine the entire drug
Side-by-side
Isomorphic Labs is the more established option (raised $2.7B); pricing is comparable on both sides.
| Metric | EvolutionaryScale | Isomorphic Labs |
|---|---|---|
| Taglinei | Frontier AI for the life sciences, enabling scientists to understand, imagine, and create proteins. | London-based AI drug-design company spun out of Google DeepMind to reimagine the entire drug |
| Foundedi | — | — |
| HQi | — | — |
| Employeesi | — | 11-50🏆 |
| Neuron scorei | 18 | 90🏆 |
| Total fundingi | Undisclosed | $2.7B🏆 |
| Latest roundi | — | Series B · May 2026 |
| Valuationi | — | — |
| Cheapest paid plani | — | Pricing not disclosed |
| Free plani | ✓ ESM3-open | ✓ |
| Free triali | ✗ | ✓ |
| Top tier pricei | ESM3 API (Closed Beta) · Contact sales | Pricing not disclosed |
| Pricing summaryi | 4 published plans | Free |
| Categoriesi |
Capability matrix
Developer-facing capabilities and access signals for EvolutionaryScale and Isomorphic Labs.
| Capability | EvolutionaryScale | Isomorphic Labs |
|---|---|---|
| MCP support | ✗ | ✗ |
| Public API | ✗ | ✗ |
| Webhooks | ✗ | ✗ |
| OAuth 2.0 | ✗ | ✗ |
| SDK languages | — | — |
| Free plan | ✓ | ✓ |
| Free trial | ✗ | ✓ |
| Verified | ✗ | ✗ |
| Active deal | ✗ | ✗ |
🟢 Strengths of EvolutionaryScale
- Strong in Drug Discovery
🔵 Strengths of Isomorphic Labs
- Has raised more capital ($2.7B vs Undisclosed)
- Higher Neuron score (90 vs 18)
- Offers a free trial
Which should you choose?
Choose Isomorphic Labs if price matters most — it starts at Free, which is friendlier for teams watching burn. Both Drug Discovery tools ship core features, so the cost delta often decides it for small teams and solo operators.
Choose Isomorphic Labs if you want the most established option — it has raised $2.7B, suggesting more runway for enterprise features, support, and long-term roadmap. For mission-critical workflows or larger teams, that stability often outweighs a lower monthly price.
Frequently asked questions
EvolutionaryScale vs Isomorphic Labs — which is better?
It depends on your priority. EvolutionaryScale is the leaner option; Isomorphic Labs has broader feature depth. See the side-by-side table above.
Is EvolutionaryScale cheaper than Isomorphic Labs?
No — Isomorphic Labs's cheapest paid plan is Free, while EvolutionaryScale's is Free.
Do EvolutionaryScale and Isomorphic Labs offer free plans?
EvolutionaryScale: Yes, has a free plan. Isomorphic Labs: Yes, has a free plan.
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