What EvolutionaryScale does

EvolutionaryScale develops frontier AI for the life sciences, centered on its ESM3 generative protein model. ESM3 reasons jointly across a protein's sequence, structure, and function, enabling scientists to understand existing proteins and design novel ones beyond those found in nature.

Key capabilities

  • Generative protein design that produces novel proteins, including ones distant from natural variants
  • Multi-modal reasoning that accepts mixed inputs of sequence, structure, or function
  • A family of model sizes trained on billions of natural proteins
  • Chain-of-thought style prompting for complex biological problems
  • Access through the Forge API and partner platforms, with a smaller open-source model under a non-commercial license

Who it's for

EvolutionaryScale targets life sciences researchers and biotechnology professionals, with open-source access for academics and enterprise access through partners such as AWS and NVIDIA. Use cases include designing enzymes for applications like carbon capture and plastic degradation, and creating novel antibodies and medicines through protein engineering.