Hyro was founded in 2018 by Israel Krush and Rom Cohen to bring controllable, safe conversational AI to enterprises, and over time it sharpened its focus on healthcare — one of the most demanding environments for automation. Health systems field enormous volumes of patient calls and messages about appointments, prescriptions, billing, and navigation, often overwhelming call centers and frustrating patients with long waits. Hyro deploys AI agents across voice, chat, and SMS to absorb that demand while keeping interactions accurate and compliant.

Hyro's platform handles patient access workflows end to end: answering common questions, routing calls to the right department, scheduling and rescheduling appointments, and managing prescription refill requests. A key differentiator is its emphasis on responsible, controllable AI — Hyro markets its approach as resistant to the hallucinations and unpredictability that make generic chatbots risky in clinical settings. The agents connect to electronic health records, scheduling systems, and IT infrastructure so they can take real actions, not just answer questions.

Because healthcare carries strict privacy and accuracy requirements, Hyro positions its AI agents as a way for health systems to improve patient access and reduce administrative load without exposing themselves to compliance or safety risks. This vertical focus lets Hyro tailor its product to the specific systems, terminology, and regulations of healthcare.

In October 2025 Hyro announced a $45 million growth round led by Healthier Capital — the fund founded by former One Medical CEO Amir Dan Rubin — with participation from Norwest, Define Ventures, Black Opal Ventures, ServiceNow Ventures, and strategic client Bon Secours Mercy Health. The round came roughly ten months after a prior raise and reportedly doubled Hyro's valuation, bringing total funding to about $95 million.

Hyro's strategy is to be the trusted AI-agent layer for patient communication across health systems, combining voice and chat automation with the safety, integrations, and domain focus that healthcare buyers require.