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OpenEvidence vs Pearl Health

Which Medical AI tool is better in 2026?

OpenEvidence

AI medical assistant for clinicians

$735M

Pearl Health

AI value-based care platform for primary care providers

$100M

Side-by-side

OpenEvidence Pearl Health
TaglineAI medical assistant for cliniciansAI value-based care platform for primary care providers
Founded20222020
HQSan Francisco, USNew York, US
Employees50-200101-200
Total funding$735M$100M
Latest roundSeries D · Jan 2026Series B · Feb 2023
Valuation$12B
Cheapest paid plan Pricing not disclosed
Free plan ✓ Free for Verified US Physicians
Free trial
Top tier price Pricing not disclosed
Pricing summary 1 published plans Risk-sharing
Categories

Capability matrix

Developer-facing capabilities and access signals for OpenEvidence and Pearl Health.

Capability OpenEvidence Pearl Health
MCP support
Public API
Webhooks
OAuth 2.0
SDK languages 2 (TypeScript, Python)
Free plan
Free trial
Verified
Active deal

🟢 Strengths of OpenEvidence

  • Has raised more capital ($735M vs $100M)
  • Offers a free plan
  • Newer company (2022)
  • Verified profile

🔵 Strengths of Pearl Health

  • Higher Neuron score (80 vs 60)
  • More mature (2020)

Which should you choose?

Choose Pearl Health if price matters most — it starts at Risk-sharing, which is friendlier for teams watching burn. Both AI Medical tools ship core features, so the cost delta often decides it for small teams and solo operators.

Choose OpenEvidence if you want the most established option — it has raised $735M, suggesting more runway for enterprise features, support, and long-term roadmap. For mission-critical workflows or larger teams, that stability often outweighs a lower monthly price.

Frequently asked questions

OpenEvidence vs Pearl Health — which is better?

It depends on your priority. OpenEvidence has raised more capital and is the more established option; Pearl Health is cheaper to start. See the side-by-side table above.

Is OpenEvidence cheaper than Pearl Health?

No — Pearl Health's cheapest paid plan is Risk-sharing, while OpenEvidence's is Free.

Do OpenEvidence and Pearl Health offer free plans?

OpenEvidence: Yes, has a free plan. Pearl Health: Paid only.

Contextual paths to related AI startups, deals and rankings.