C the Signs vs OpenEvidence
Which Healthcare AI tool is better in 2026?
C the Signs
AI platform that identifies patients at risk of cancer at the earliest, most curable stage
OpenEvidence
AI medical assistant for clinicians
Side-by-side
OpenEvidence is the more established option (raised $735M); pricing is comparable on both sides.
| Metric | C the Signs | OpenEvidence |
|---|---|---|
| Taglinei | AI platform that identifies patients at risk of cancer at the earliest, most curable stage | AI medical assistant for clinicians |
| Foundedi | — | 2022🏆 |
| HQi | — | San Francisco, US |
| Employeesi | 11-50 | 50-200🏆 |
| Neuron scorei | 41 | 63🏆 |
| Total fundingi | $8M | $735M🏆 |
| Latest roundi | Venture | Series D · Jan 2026 |
| Valuationi | — | $12B🏆 |
| Cheapest paid plani | Pricing not disclosed | — |
| Free plani | ✓ | ✗ |
| Free triali | ✓ | ✗ |
| Top tier pricei | Pricing not disclosed | Enterprise · Contact sales |
| Pricing summaryi | Free | 1 published plans |
| Categoriesi |
Capability matrix
Developer-facing capabilities and access signals for C the Signs and OpenEvidence.
| Capability | C the Signs | OpenEvidence |
|---|---|---|
| MCP support | ✗ | ✗ |
| Public API | ✗ | ✓ |
| Webhooks | ✗ | ✗ |
| OAuth 2.0 | ✗ | ✗ |
| SDK languages | — | 2 (TypeScript, Python) |
| Free plan | ✓ | ✗ |
| Free trial | ✓ | ✗ |
| Verified | ✗ | ✓ |
| Active deal | ✗ | ✗ |
🟢 Strengths of C the Signs
- Offers a free plan
- Offers a free trial
🔵 Strengths of OpenEvidence
- Has raised more capital ($735M vs $8M)
- Higher Neuron score (63 vs 41)
- Newer company (2022)
- Verified profile
Which should you choose?
Choose OpenEvidence if price matters most — it starts at Freemium, which is friendlier for teams watching burn. Both AI Healthcare tools ship core features, so the cost delta often decides it for small teams and solo operators.
Choose OpenEvidence if you want the most established option — it has raised $735M, suggesting more runway for enterprise features, support, and long-term roadmap. For mission-critical workflows or larger teams, that stability often outweighs a lower monthly price.
Frequently asked questions
C the Signs vs OpenEvidence — which is better?
It depends on your priority. C the Signs is the leaner option; OpenEvidence has broader feature depth. See the side-by-side table above.
Is C the Signs cheaper than OpenEvidence?
No — OpenEvidence's cheapest paid plan is Freemium, while C the Signs's is Free.
Do C the Signs and OpenEvidence offer free plans?
C the Signs: Yes, has a free plan. OpenEvidence: Paid only.
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